Difference between revisions of "Organization of genetics topics"
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The topics I would like an introductory genetics class to cover (or at least touch on in an introductory sense) include: | The topics I would like an introductory genetics class to cover (or at least touch on in an introductory sense) include: | ||
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*classical genetics | *classical genetics | ||
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**distinction between the germ-line and the soma | **distinction between the germ-line and the soma | ||
*molecular genetics | *molecular genetics | ||
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**gene structure, gene expression regulation, protein structure, and the central dogma | **gene structure, gene expression regulation, protein structure, and the central dogma | ||
**genome structure and organization | **genome structure and organization | ||
**types of mutations and their effects | **types of mutations and their effects | ||
| + | **metabolic pathways, developmental pathways, and epistasis | ||
**transposable elements and other forms of selfish genes | **transposable elements and other forms of selfish genes | ||
**genotype/phenotype association tests | **genotype/phenotype association tests | ||
| + | **comparison of model organisms and viral versus bacterial versus eukaryotic genetics | ||
**methods of genetic engineering and germ line transformation | **methods of genetic engineering and germ line transformation | ||
**genetic tools such as binary expression systems, PCR, Sanger sequencing, next generation sequencing, restriction endonucleases, and plasmid engineering, FISH, probes, chip hybridization | **genetic tools such as binary expression systems, PCR, Sanger sequencing, next generation sequencing, restriction endonucleases, and plasmid engineering, FISH, probes, chip hybridization | ||
**forward genetics and reverse genetics | **forward genetics and reverse genetics | ||
| + | **X-inactivation, imprinting and epigenetics | ||
*population genetics | *population genetics | ||
| + | **inbreeding and population structure | ||
| + | **average heterozygosity and effective population size, the coalescent | ||
| + | **selection and genetic drift | ||
| + | **tests of neutrality | ||
*quantitative genetics | *quantitative genetics | ||
| − | *evolutionary | + | **parent-offspring regression |
| + | **heritability and phenotype variance | ||
| + | **breeder's equation | ||
| + | **twin studies | ||
| + | *evolutionary genetics | ||
| + | **species phylogeny | ||
| + | **gene evolution and gene families | ||
| + | **evo-devo | ||
*supporting statistical logic | *supporting statistical logic | ||
**probability rules | **probability rules | ||
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**the chi-square test and degrees of freedom | **the chi-square test and degrees of freedom | ||
**linear regression | **linear regression | ||
| + | **means and variance | ||
*interdisciplinary | *interdisciplinary | ||
**the history of eugenics and current laws regarding genetic data | **the history of eugenics and current laws regarding genetic data | ||
Revision as of 12:51, 22 August 2014
I am interested in what people thin the best organization of genetics topics might be.
Genetics is a vast, rapidly changing field. There are connections to other diverse fields such as psychology, law, medicine, history, and teaching. A classic way to divide genetics topics is into classical, molecular, and population genetics; however, I suspect this leaves out important areas.
The topics I would like an introductory genetics class to cover (or at least touch on in an introductory sense) include:
- classical genetics
- Mendelian Inheritance and Punnet squares
- Complementation tests
- Genetic linkage and recombination
- Punnet squares and epistasis
- alleles and morphs
- penetrance and expressivity
- pedigree analysis
- LOD scores
- cytological genetics
- chromosomes, mitosis and meiosis, nondisjunction, aneuploidy, polyploidy
- sex chromosomes and sex determination systems
- aneuploidy and polyploidy
- distinction between the germ-line and the soma
- molecular genetics
- gene structure, gene expression regulation, protein structure, and the central dogma
- genome structure and organization
- types of mutations and their effects
- metabolic pathways, developmental pathways, and epistasis
- transposable elements and other forms of selfish genes
- genotype/phenotype association tests
- comparison of model organisms and viral versus bacterial versus eukaryotic genetics
- methods of genetic engineering and germ line transformation
- genetic tools such as binary expression systems, PCR, Sanger sequencing, next generation sequencing, restriction endonucleases, and plasmid engineering, FISH, probes, chip hybridization
- forward genetics and reverse genetics
- X-inactivation, imprinting and epigenetics
- population genetics
- inbreeding and population structure
- average heterozygosity and effective population size, the coalescent
- selection and genetic drift
- tests of neutrality
- quantitative genetics
- parent-offspring regression
- heritability and phenotype variance
- breeder's equation
- twin studies
- evolutionary genetics
- species phylogeny
- gene evolution and gene families
- evo-devo
- supporting statistical logic
- probability rules
- binomial distributions
- normal distribution
- Poisson distribution
- the chi-square test and degrees of freedom
- linear regression
- means and variance
- interdisciplinary
- the history of eugenics and current laws regarding genetic data
- GMO crops including examples, methods, ethics, and economics
- genetic pest management
- medical and cancer genetics
- personal genomics
- developmental genetics
- genetic anthropology
