Difference between revisions of "Mutation"
From Genetics Wiki
(Created page with "All natural variation originates from mutations. etc. =Types of Mutations= =Mutation Rates= =Directional Mutation Model= <math>p_g = p_{g-1} (1-\mu)</math> <math>p_g =...") |
(→Directional Mutation Model) |
||
| Line 12: | Line 12: | ||
<math>p_g = p_0 e^{-\mu g}</math> | <math>p_g = p_0 e^{-\mu g}</math> | ||
| + | |||
| + | As a rule of thumb the time until loss of half of the non-mutated alleles is approximately 70% of the "one out of x" mutation rate. If a gene region has a mutation rate of one out of 100,000 then approximately half of the copies will mutate in 70,000 generations. | ||
=Reversible Mutation Model= | =Reversible Mutation Model= | ||
Revision as of 17:27, 3 February 2016
All natural variation originates from mutations. etc.
Contents
Types of Mutations
Mutation Rates
Directional Mutation Model
[math]p_g = p_{g-1} (1-\mu)[/math]
[math]p_g = p_0 (1-\mu)^g[/math]
[math]p_g = p_0 e^{-\mu g}[/math]
As a rule of thumb the time until loss of half of the non-mutated alleles is approximately 70% of the "one out of x" mutation rate. If a gene region has a mutation rate of one out of 100,000 then approximately half of the copies will mutate in 70,000 generations.
Reversible Mutation Model
[math]p_g = p_{g-1} (1-\mu) + (1-p_{g-1})\nu[/math]
[math]\hat{p} = \frac{\nu}{\nu+\mu}[/math]
