Difference between revisions of "Organization of genetics topics"

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*gene structure, gene expression regulation, protein structure, and the central dogma
 
*gene structure, gene expression regulation, protein structure, and the central dogma
 
*genome structure and organization
 
*genome structure and organization
*chromosomes, mitosis and meiosis, nondisjunction
+
*chromosomes, mitosis and meiosis, nondisjunction, aneuploidy, polyploidy
 
*sex chromosomes and sex determination systems
 
*sex chromosomes and sex determination systems
 
*aneuploidy and polyploidy
 
*aneuploidy and polyploidy
Line 32: Line 32:
 
*genetic anthropology
 
*genetic anthropology
 
*inbreeding and population structure
 
*inbreeding and population structure
*average heterozygosity and effective population size
+
*average heterozygosity and effective population size, the coalescent
 
*X-inactivation, imprinting and epigenetics
 
*X-inactivation, imprinting and epigenetics
 +
*species phylogenies
 +
*selection and genetic drift
 +
*probability rules
 +
*binomial distributions
 +
*normal distribution
 +
*Poisson distribution
 
*---to be continued---
 
*---to be continued---

Revision as of 12:07, 22 August 2014

I am interested in what people thin the best organization of genetics topics might be.

Genetics is a vast, rapidly changing field. There are connections to other diverse fields such as psychology, law, medicine, history, and teaching. A classic way to divide genetics topics is into classical, molecular, and population genetics; however, I suspect this leaves out important areas.

The topics I would like an introductory genetics class to cover include:

  • Mendelian Inheritance and Punnet Squares
  • Complementation tests
  • Genetic linkage and recombination
  • metabolic pathways and epistasis
  • gene structure, gene expression regulation, protein structure, and the central dogma
  • genome structure and organization
  • chromosomes, mitosis and meiosis, nondisjunction, aneuploidy, polyploidy
  • sex chromosomes and sex determination systems
  • aneuploidy and polyploidy
  • distinction between the germ-line and the soma
  • mutations and their effects
  • alleles and morphs
  • penetrance and expressivity
  • transposable elements
  • pedigree analysis
  • LOD scores
  • the chi-square test and degrees of freedom
  • quantitative genetics of complex traits and the regression
  • methods of genetic engineering and germ line transformation
  • genetic tools such as binary expression systems, PCR, Sanger sequencing, next generation sequencing, restriction endonucleases, and plasmid engineering
  • forward genetics and reverse genetics
  • personal genomics
  • introductory developmental genetics
  • the history of eugenics and laws regarding genetic data
  • genetic pest management and selfish genes
  • medical and cancer genetics
  • genetic anthropology
  • inbreeding and population structure
  • average heterozygosity and effective population size, the coalescent
  • X-inactivation, imprinting and epigenetics
  • species phylogenies
  • selection and genetic drift
  • probability rules
  • binomial distributions
  • normal distribution
  • Poisson distribution
  • ---to be continued---