Difference between revisions of "Classical Genetics"
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In classical genetics no molecular methods are required. You work with easily observable phenotypes and, to a degree, control the crosses that occur. Classical genetics developed a powerful framework of logic that allowed mechanisms of inheritance and gene interactions, that were not directly observable at the time, to be inferred to exist. | In classical genetics no molecular methods are required. You work with easily observable phenotypes and, to a degree, control the crosses that occur. Classical genetics developed a powerful framework of logic that allowed mechanisms of inheritance and gene interactions, that were not directly observable at the time, to be inferred to exist. | ||
| − | The concept of true breeding "parental" lines, F<sub>1</sub> and F<sub>2</sub> crosses, Mendel's laws, and tools such as the Punnet square are used in classical genetics. This is also where definitions of dominance and epistatic interactions originate. | + | The concept of true breeding "parental" lines, F<sub>1</sub> and F<sub>2</sub> crosses, Mendel's laws, and tools such as the Punnet square are used in classical genetics. This is also where definitions of [[dominance]] and epistatic interactions originate. |
Moving into more modern classical genetics the field developed linkage mapping, test crosses, non-disjunction, and how these related to meiosis and genes physical location on chromosomes. | Moving into more modern classical genetics the field developed linkage mapping, test crosses, non-disjunction, and how these related to meiosis and genes physical location on chromosomes. | ||
Revision as of 19:51, 13 July 2014
Classical genetics refers to "garden experiments" in patterns of heredity and is how the field of genetics began.
In classical genetics no molecular methods are required. You work with easily observable phenotypes and, to a degree, control the crosses that occur. Classical genetics developed a powerful framework of logic that allowed mechanisms of inheritance and gene interactions, that were not directly observable at the time, to be inferred to exist.
The concept of true breeding "parental" lines, F1 and F2 crosses, Mendel's laws, and tools such as the Punnet square are used in classical genetics. This is also where definitions of dominance and epistatic interactions originate.
Moving into more modern classical genetics the field developed linkage mapping, test crosses, non-disjunction, and how these related to meiosis and genes physical location on chromosomes.
