Difference between revisions of "Inbreeding (population sense)"
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<math>H_S = 2 p (1 - p) </math> is the expected frequency of heterozygous genotypes in a popualtion. In this example it is given for the case where there are only two alleles. (<math>S</math> refers to Subpopulation.) | <math>H_S = 2 p (1 - p) </math> is the expected frequency of heterozygous genotypes in a popualtion. In this example it is given for the case where there are only two alleles. (<math>S</math> refers to Subpopulation.) | ||
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| + | <math>F_{IS}</math> can be incorporated into expectations of genotype frequencies by adjusting Hardy–Weinberg proportions. | ||
Revision as of 22:35, 22 January 2016
An assumption of Hardy–Weinberg genotype proportions is alleles are paired independently of each other. This can be referred to as random mating in a popualtion.
[math]F_{IS} = \frac{H_S - H_I}{H_S}[/math]
where
[math]H_I[/math] is the observed frequency of heterozygous genotypes in a popualtion. ([math]I[/math] refers to Individual.)
[math]H_S = 2 p (1 - p) [/math] is the expected frequency of heterozygous genotypes in a popualtion. In this example it is given for the case where there are only two alleles. ([math]S[/math] refers to Subpopulation.)
[math]F_{IS}[/math] can be incorporated into expectations of genotype frequencies by adjusting Hardy–Weinberg proportions.
