Difference between revisions of "Mutation"
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<math>\hat{p} = \frac{\nu}{\nu+\mu}</math> | <math>\hat{p} = \frac{\nu}{\nu+\mu}</math> | ||
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| + | =Jukes-Cantor Model= | ||
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| + | =Molecular Clock= | ||
Latest revision as of 04:04, 5 February 2016
All natural variation originates from mutations. etc.
Contents
Types of Mutations
Mutation Rates
Directional Mutation Model
[math]p_g = p_{g-1} (1-\mu)[/math]
[math]p_g = p_0 (1-\mu)^g[/math]
[math]p_g = p_0 e^{-\mu g}[/math]
As a rule of thumb the time until loss of half of the non-mutated alleles is approximately 70% of the "one out of x" mutation rate. If a gene region has a mutation rate of one out of 100,000 then approximately half of the copies will mutate in 70,000 generations.
Reversible Mutation Model
[math]p_g = p_{g-1} (1-\mu) + (1-p_{g-1})\nu[/math]
[math]\hat{p} = \frac{\nu}{\nu+\mu}[/math]
