Difference between revisions of "Kimura 1968"

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(Paragraph Four)
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*Genome size estimate <math>=4\times10^9</math> bp.
 
*Genome size estimate <math>=4\times10^9</math> bp.
 
*Gene size coreesponding to 100 amino acids <math>=300</math> bp.
 
*Gene size coreesponding to 100 amino acids <math>=300</math> bp.
 +
*Adjustment to also include synonymous mutations that do not change the amino acid <math>1 + 0.2 = 1.2</math>
  
 
[[Category:Publication]]
 
[[Category:Publication]]

Revision as of 13:16, 15 September 2018

Citation

Kimura, M. (1968). Evolutionary rate at the molecular level. Nature, 217(5129), 624-626.

Links

Notes

Paragraph Four

Kimura constructs an estimate of the rate of genome-wide nucleotide substitutions based on observed amino acid differences between species.

  • Average years between amino acid substitutions in 100 amino acids [math]=28\times10^6[/math] a.
  • Genome size estimate [math]=4\times10^9[/math] bp.
  • Gene size coreesponding to 100 amino acids [math]=300[/math] bp.
  • Adjustment to also include synonymous mutations that do not change the amino acid [math]1 + 0.2 = 1.2[/math]