Difference between revisions of "McMeniman et al. 2009"
(Created page with "=Citation= McMeniman, C. J., Lane, R. V., Cass, B. N., Fong, A. W., Sidhu, M., Wang, Y. F., & O'neill, S. L. (2009). Stable introduction of a life-shortening Wolbachia infecti...") |
(No difference)
|
Latest revision as of 21:00, 6 October 2018
Citation
McMeniman, C. J., Lane, R. V., Cass, B. N., Fong, A. W., Sidhu, M., Wang, Y. F., & O'neill, S. L. (2009). Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti. Science, 323(5910), 141-144.
Link
http://science.sciencemag.org/content/323/5910/141
Published Abstract
Most pathogens require a relatively long period of development in their mosquito vector before they can be transmitted to a new human host; hence, only older insects are of epidemiological importance. The successful transfer of a life-shortening strain of the inherited bacterial symbiont, Wolbachia, into the major mosquito vector of dengue, Aedes aegypti, halved adult life span under laboratory conditions. The association is stable, and the Wolbachia strain is maternally inherited at high frequency. It is capable of inducing complete cytoplasmic incompatibility, which should facilitate its invasion into natural field populations and its persistence over time. Our data suggest that targeting mosquito age with inherited Wolbachia infections may be a viable strategy to reduce the transmission of pathogens such as dengue viruses.
