Kimura 1968

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Citation

Kimura, M. (1968). Evolutionary rate at the molecular level. Nature, 217(5129), 624-626.

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Notes

Paragraph Four

Kimura constructs an estimate of the rate of genome-wide nucleotide substitutions based on observed amino acid differences between species.

  • Average years between amino acid substitutions in 100 amino acids [math]=28\times10^6[/math] a.
  • Genome size estimate [math]=4\times10^9[/math] bp.
  • Gene size coreesponding to 100 amino acids [math]=300[/math] bp.