Difference between revisions of "Reed and Tishkoff 2006a"
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Latest revision as of 03:33, 7 October 2018
Citation
Reed, F. A., & Tishkoff, S. A. (2006). Positive selection can create false hotspots of recombination. Genetics, 172(3), 2011-2014.
Links
- http://www.genetics.org/content/172/3/2011.short
- http://hawaiireedlab.com/pdf/r/reedandtishkoff2006a.pdf (internal lab link only)
Published Abstract
Simulations of positive directional selection, under parameter values appropriate for approximating human genetic diversity and rates of recombination, reveal that the effects of strong selective sweeps on patterns of linkage disequilibrium (LD) mimic the pattern expected with recombinant hotspots.
