===Huang et al. 2005=== Huang, Y., Chiang, C. Y., Lee, S. K., Gao, Y., Hu, E. L., Yoreo, J. D., & Belcher, A. M. (2005). Programmable assembly of nanoarchitectures using genetically engineered viruses. //Nano Letters//, 5(7), 1429--1434. ==Links== * https://pubs.acs.org/doi/abs/10.1021/nl050795d * https://scholar.google.com/scholar?cluster=13034910918052042101 * {{private:huangetal2005.pdf}} (internal lab link) ==Abstract== Biological systems possess inherent molecular recognition and self-assembly capabilities and are attractive templates for constructing complex material structures with molecular precision. Here we report the assembly of various nanoachitectures including nanoparticle arrays, hetero-nanoparticle architectures, and nanowires utilizing highly engineered M13 bacteriophage as templates. The genome of M13 phage can be rationally engineered to produce viral particles with distinct substrate-specific peptides expressed on the filamentous capsid and the ends, providing a generic template for programmable assembly of complex nanostructures. Phage clones with gold-binding motifs on the capsid and streptavidin-binding motifs at one end are created and used to assemble Au and CdSe nanocrytals into ordered one-dimensional arrays and more complex geometries. Initial studies show such nanoparticle arrays can further function as templates to nucleate highly conductive nanowires that are important for addressing/interconnecting individual nanostructures. {{tag>Publication}}