===Seager and Ayala 1982===
Seager, R. D., & Ayala, F. J. (1982). Chromosome interactions in //Drosophila melanogaster//. I. Viability studies. //Genetics//, 102(3), 467--483.

==Links==
  * https://www.genetics.org/content/102/3/467.short
  * https://scholar.google.com/scholar?cluster=1380904317487839071
  * {{private:seagerandayala1982.pdf}} (internal lab link)

==Abstract==
The nature of fitness interactions is an important, yet unsolved, question in population genetics. We compare the egg-to-adult viability of individuals homozygous for either a second or a third chromosome with the viability of individuals homozygous for both chromosomes simultaneously. On the average, the viability of the two-chromosome homozygotes is somewhat greater than expected assuming that the fitnesses of the single-chromosome homozygotes interact in a multiplicative fashion. This result differs from previous observations that indicate either no significant deviations from the expectation or lower-than-expected average fitnesses for the double homozygotes.

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