Difference between revisions of "Population Genetics"
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Under neutrality are small spikes of high diversity that contribute more to PC loading and tend to be shared between populations expected from older coalescent regions (and the high variance of the coalescent process) because there is more time for both mutation (high diversity), recombination (small regions), and gene flow or shared ancestry (found across populations). | Under neutrality are small spikes of high diversity that contribute more to PC loading and tend to be shared between populations expected from older coalescent regions (and the high variance of the coalescent process) because there is more time for both mutation (high diversity), recombination (small regions), and gene flow or shared ancestry (found across populations). | ||
| − | =[[Mutation-Drift Equilibrium]] | + | =Topics= |
| − | + | *[[Coalescence]] | |
| − | + | *[[Mutation-Drift Equilibrium]] | |
| − | + | *[[Selective Sweeps]] | |
| − | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607448/ | + | **https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607448/ |
| − | + | *[[ABBA BABA Test]] | |
| − | + | **http://evomics.org/learning/population-and-speciation-genomics/2018-population-and-speciation-genomics/abba-baba-statistics/ | |
| − | + | **http://coleoguy.blogspot.com/2013/05/abba-baba.html | |
| − | http://evomics.org/learning/population-and-speciation-genomics/2018-population-and-speciation-genomics/abba-baba-statistics/ | + | **https://academic.oup.com/mbe/article/32/1/244/2925550 |
| − | + | **https://www.nature.com/articles/nrg3446 | |
| − | http://coleoguy.blogspot.com/2013/05/abba-baba.html | ||
| − | |||
| − | https://academic.oup.com/mbe/article/32/1/244/2925550 | ||
| − | |||
| − | https://www.nature.com/articles/nrg3446 | ||
=Reading= | =Reading= | ||
Revision as of 01:26, 18 September 2018
Under neutrality are small spikes of high diversity that contribute more to PC loading and tend to be shared between populations expected from older coalescent regions (and the high variance of the coalescent process) because there is more time for both mutation (high diversity), recombination (small regions), and gene flow or shared ancestry (found across populations).
Topics
Reading
http://www.genetics.org/content/205/3/1003
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448894/
https://www.nature.com/articles/hdy201655
https://academic.oup.com/aobpla/article/doi/10.1093/aobpla/plv026/200461
https://onlinelibrary.wiley.com/doi/full/10.1111/mam.12052
https://www.nature.com/subjects/population-genetics
https://www.cell.com/trends/ecology-evolution/abstract/S0169-5347(14)00223-7
Dobzhansky, T. (1955, January). A review of some fundamental concepts and problems of population genetics. In Cold Spring Harbor Symposia on Quantitative Biology (Vol. 20, pp. 1-15). Cold Spring Harbor Laboratory Press.
Chakravarti, A. (1999). Population genetics—making sense out of sequence. Nature genetics, 21(1s), 56.
Lanfear, R., Kokko, H., & Eyre-Walker, A. (2014). Population size and the rate of evolution. Trends in ecology & evolution, 29(1), 33-41.
Lek, M., Karczewski, K. J., Minikel, E. V., Samocha, K. E., Banks, E., Fennell, T., ... & Tukiainen, T. (2016). Analysis of protein-coding genetic variation in 60,706 humans. Nature, 536(7616), 285.
Charlesworth, B., & Charlesworth, D. (2017). Population genetics from 1966 to 2016. Heredity, 118(1), 2.
Casillas, S., & Barbadilla, A. (2017). Molecular population genetics. Genetics, 205(3), 1003-1035.
Schrider, D. R., & Kern, A. D. (2018). Supervised machine learning for population genetics: a new paradigm. Trends in Genetics.
Habel, J. C., Zachos, F. E., Dapporto, L., Roedder, D., Radespiel, U., Tellier, A., & Schmitt, T. (2015). Population genetics revisited–towards a multidisciplinary research field. Biological Journal of the Linnean Society, 115(1), 1-12. [1]
Dlugosch, K. M., Anderson, S. R., Braasch, J., Cang, F. A., & Gillette, H. D. (2015). The devil is in the details: genetic variation in introduced populations and its contributions to invasion. Molecular ecology, 24(9), 2095-2111.
Cvijović, I., Ba, A. N. N., & Desai, M. M. (2018). Experimental Studies of Evolutionary Dynamics in Microbes. Trends in Genetics.
Hardy, G. H. (1908) Mendelian Proportions in a mixed population. Science 28(706): 49-50.
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