Silver 1993

Reference

Silver, L. M. (1993). The peculiar journey of a selfish chromosome: mouse t haplotypes and meiotic drive. Trends in Genetics, 9(7), 250-254.

Links

• https://www.sciencedirect.com/science/article/pii/0168952593900905
• http://hawaiireedlab.com/pdf/s/silver1993.pdf (internal lab link only)

Published Abstract

Mouse t haplotypes are descendents of a variant form of chromosome 17 that evolved the ability to propagate itself at the expense of the wild-type homolog from heterozygous +/t males. Although once enigmatic, these widespread selfish chromosomes have revealed many of their secrets in response to a combined assault with molecular, genetic and phylogenetic techniques. This review summarizes the current understanding of t haplotypes and their raison d'être.