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floyd_reed

Introduction

Hello world. I am Floyd A. Reed. I am currently an associate professor in the Department of Biology at the University of Hawaiʻi at Mānoa in Honolulu. My training is in Drosophila (fruit fly) and human population genetics; however, my work is defined by what I do which evolves over time. I do not limit our lab work to a particular theme and the best way to see what we have successfully completed is to look through our publications. Here in Hawaiʻi my lab is working on a wide range of organisms using molecular genetic and population genetic tools. I am a strong believer in student self-determination and, right or wrong, I expect my graduate students to bring their own questions to work on in the lab and so far they have had an excellent track record of raising their own research funding. I feel that in the long run this is better for me (in terms of broadening my focus) and for them in terms of developing their own future research directions. In the process I have had graduate students work on human genetics in West Africa, population genomics of sea urchins, Hawaiian honeycreeper microbiota, novel sponges found in Hawaiʻi, and hybridization in Central American crocodiles.

I also have had several postdocs and collaborators with the main goal of developing genetic pest management tools for mosquitoes in Hawaiʻi and more broadly for applications across the Indo-Pacific.

Publications

Genetic Pest Management

  • Reed, F. A., Aquino-Michaels, T. G., Costantini, M. S., Láruson, Á. J., & Sutton, J. T. (2018). RPM-Drive: A robust, safe, and reversible gene drive system that remains functional after 200+ generations. arXiv preprint arXiv:1806.05304.
  • Reed, F. A. (2017). CRISPR/Cas9 gene drive: Growing pains for a new technology. Genetics, 205(3), 1037.
  • Reed, F. A. (2017). Evolutionary Genetic Engineering in the Indo-Pacific: Conservation, Humanitarian, and Social Issues. arXiv preprint arXiv:1706.01710.
  • Gokhale, C. S., Reeves, R. G., & Reed, F. A. (2014). Dynamics of a combined medea-underdominant population transformation system. BMC Evolutionary Biology, 14(1), 98.
  • Reeves, R. G., Bryk, J., Altrock, P. M., Denton, J. A., & Reed, F. A. (2014). First steps towards underdominant genetic transformation of insect populations. PLoS One, 9(5), e97557.
  • Reeves, R. G., Denton, J. A., Santucci, F., Bryk, J., & Reed, F. A. (2012). Scientific standards and the regulation of genetically modified insects. PLoS Neglected Tropical Diseases, 6(1), e1502.
  • Altrock, P. M., Traulsen, A., & Reed, F. A. (2011). Stability properties of underdominance in finite subdivided populations. PLoS Computational Biology, 7(11), e1002260.
  • Altrock, P. M., Traulsen, A., Reeves, R. G., & Reed, F. A. (2010). Using underdominance to bi-stably transform local populations. Journal of Theoretical Biology, 267(1), 62–75.

Transcriptomics

  • Láruson, Á. J., Coppard, S. E., Pespeni, M. H., & Reed, F. A. (2018). Gene expression across tissues, sex, and life stages in the sea urchin Tripneustes gratilla [Toxopneustidae, Odontophora, Camarodonta]. Marine Genomics, 41, 12–18.
  • Bryk, J., Reeves, R. G., Reed, F. A., & Denton, J. A. (2017). Transcriptional effects of a positive feedback circuit in Drosophila melanogaster. BMC Genomics, 18(1), 990.

Genome Wide Association Studies

  • Kingston, S. E., Martino, P., Melendy, M., Reed, F. A., & Carlon, D. B. (2018). Linking genotype to phenotype in a changing ocean: inferring the genomic architecture of a blue mussel stress response with genome‐wide association. Journal of Evolutionary Biology, 31(3), 346–361.

Population Genetics

  • Pending ca. 2020. Láruson, Á. J., & Reed, F. A. Population Genetics with R: A Practical Guide. Writing contract with Oxford University Press.
  • Láruson, Á. J., & Reed, F. A. (2016). Stability of underdominant genetic polymorphisms in population networks. Journal of Theoretical Biology, 390, 156–163.
  • Reed, F. A., Traulsen, A, & Altrock, P M. (2013) Underdominance. In Encyclopedia of Genetics, Brenner, S. & Miller, J. H., Eds., Elsevier Science, Inc.
  • Stemshorn, K. C., Reed, F. A., Nolte, A. W., & Tautz, D. (2011). Rapid formation of distinct hybrid lineages after secondary contact of two fish species (Cottus sp.). Molecular Ecology, 20(7), 1475–1491.
  • Haubold, B., Reed, F. A., & Pfaffelhuber, P. (2010). Alignment-free estimation of nucleotide diversity. Bioinformatics, 27(4), 449–455.
  • Reed, F. A. (2007). Two-locus epistasis with sexually antagonistic selection: A genetic Parrondo's paradox. Genetics, 176(3), 1923–1929.
  • Reed, F. A., & Tishkoff, S. A. (2006). Positive selection can create false hotspots of recombination. Genetics, 172(3), 2011–2014.
  • Reed, F. A., Reeves, R. G., & Aquadro, C. F. (2005). Evidence of susceptibility and resistance to cryptic X‐linked meiotic drive in natural populations of Drosophila melanogaster. Evolution, 59(6), 1280–1291.
  • Aquadro, C. F., DuMont, V. B., & Reed, F. A. (2001). Genome-wide variation in the human and fruitfly: a comparison. Current Opinion in Genetics & Development, 11(6), 627–634.

Conservation Genetics

  • Shafer, A. B., Wolf, J. B., Alves, P. C., Bergström, L., Bruford, M. W., Brännström, I., … & Fawcett, K. D. (2015). Genomics and the challenging translation into conservation practice. Trends in Ecology & Evolution, 30(2), 78–87.
    • Shafer, A. B., Wolf, J. B., Alves, P. C., Bergström, L., Colling, G., Dalén, L., … & Hoezel, A. R. (2016). Reply to Garner et al. Trends in Ecology & Evolution, 31(2), 83–84.

Drosophila Genetics

Human Genetics

Game Theory

  • Traulsen, A., & Reed, F. A. (2012). From genes to games: cooperation and cyclic dominance in meiotic drive. Journal of Theoretical Biology, 299, 120–125.
  • Milinski, M., Sommerfeld, R. D., Krambeck, H. J., Reed, F. A., & Marotzke, J. (2008). The collective-risk social dilemma and the prevention of simulated dangerous climate change. Proceedings of the National Academy of Sciences, 105(7), 2291–2294.

Forensics

  • Kontanis, E. J., & Reed, F. A. (2006). Evaluation of real‐time PCR amplification efficiencies to detect PCR inhibitors. Journal of Forensic Sciences, 51(4), 795–804.
floyd_reed.txt · Last modified: 2019/10/09 17:38 by floyd