Floyd A. Reed

Hello world!  My professional interests revolve around the process and dynamics of evolution.  My actual work focuses on genetics but other areas of evolution are also fascinating to me, from cultural inheritance in humans and other animals, to "artificial life" in computer simulations, game theory dynamics, machine learning and even evolvable hardware.

I also have a long term interest in learning about human history in particular in Africa and Oceania, where modern humans have existed for a very long time and  where we stand the most to learn from genetic studies, and a long term interest in both the demographic and selective (both adaptive and non-adaptive) processes in how a population or species evolves.  I have more recent active interests (since 2006) in using evolutionary processes to genetically engineer populations for applications in species conservation and breaking cycles of disease transmission.

Professional CV

Education
Ph.D.  2004  Cornell University (Wikipedia) part of the Ivy League.
Dept. of Molecular Biology and Genetics
Adviser: Dr. Charles "Chip" Aquadro (Population Genetics)
Committee Member: Dr. Richard T. Durrett (Applied Math minor)
Committee Member: Dr. Richard Harrison (Ecology and Evolution minor)
Committee Member: Dr. Ken Kennedy (Physical Anthropology minor)

B.A. (Hons)  1996  Warren Wilson College (Wikipedia) part of the Work Colleges Consortium.
Biology and Chemistry double major (also completed all of the requirements for a physics minor, not awarded because of substantial coursework overlap with the chemistry major)
Adviser: Dr. Lee Swendsen
College Print Shop work crew
Supervisor: Rev. George "Pete" Tolleson

Work

Publications  (link to Google Scholar profile)

2016 Láruson, Á. J., and F. A. Reed. Stability of underdominant genetic polymorphisms in population networks. Journal of Theoretical Biology 390: 156-163. doi:10.1016/j.jtbi.2015.11.023

2016 A Shafer, JBW Wolf, PC Alves, L Bergström, G Colling, L Dalén, et al. Reply to Garner et al. Trends in Ecology & Evolution 31 (2), 83-84. doi:10.1016/j.tree.2015.11.010

2015 Shafer, A. B. A., J. B. W. Wolf, P. C. Alves, L. Bergström, M. W. Bruford, I. Brännström, et al. Genomics and the challenging translation into conservation practice. Trends in Ecology & Evolution 30 (2), 78-87. doi:10.1016/j.tree.2014.11.009

2014 Gokhale, C., R. G. Reeves, and F. A. Reed. Dynamics of a combined medea-underdominant population transformation system. BMC Evolutionary Biology 14: 90. doi:10.1186/1471-2148-14-98

2014 Reeves, R. G., J. Bryk, P. M. Altrock, J. Denton, and F. A. Reed. First Steps towards Underdominant Genetic Transformation of Insect Populations. PLoS ONE 9: e97557. doi:10.1371/journal.pone.0097557

2014. Tabios, M., L. Boell, and F. A. Reed. A new mutation of PDA synthase, sepia, isolated from wild Drosophila melanogaster. Drosophila Information Service 97: 176-177. http://www.ou.edu/journals/dis/DIS97/Tabios%20176.pdf

2013 Reed, F. A., A. Traulsen, P. M. Altrock Underdominance. In “Encyclopedia of Genetics” S. Brenner & J. H. Miller Eds., Elsevier Science Inc. doi:10.1016/B978-0-12-374984-0.01601-6

2012 Reeves, R. G., J. Denton, F. Santucci, J. Bryk, and F. A. Reed. Scientific Standards and the Regulation of Genetically Modified Insects. PLoS Neglected Tropical Diseases 6: e1502. doi:10.1371/journal.pntd.0001502

2012 Reed, F.A. Modern Human Migrations: The First 200,000 Years. In “Migrations: Interdisciplinary Perspectives” M. Messer, R. Schroeder & R. Wodak Eds., Springer. doi:10.1007/978-3-7091-0950-2_29

2012 Traulsen, A. and F. A. Reed. From genes to games: Cooperation and cyclic dominance of meiotic drive alleles. Journal of Theoretical Biology 299: 120-125. doi:10.1016/j.jtbi.2011.04.032

2011. Haubold, B., F. A. Reed and P. Pfaffelhuber. Alignment-free estimation of nucleotide diversity. Bioinformatics 27: 449-455. doi:10.1093/bioinformatics/btq689

2011. Stemshorn, K. C., F. A. Reed, A. W. Nolte, and D. Tautz. Rapid formation of distinct hybrid lineages after secondary contact of two fish species (Cottus sp.). Molecular Ecology 20: 1475-1491. doi:10.1111/j.1365-294X.2010.04997.x

2011 Altrock, P. M., A. Traulsen, and F. A. Reed. Stability Properties of Underdominance in Finite Subdivided Populations. PLoS Computational Biology 7: e1002260. doi:10.1371/journal.pcbi.1002260

2010 Altrock, P. M., A. Traulsen, R. G. Reeves, and F. A. Reed. Using underdominance to bi-stably transform local populations. Journal of Theoretical Biology 267: 62-75. doi:10.1016/j.jtbi.2010.08.004

2010. Allaby, R. G., F. R. Friedlaender, F. A. Reed, K. K. Kidd, J. R. Kidd, et al. Prehistoric Pacific Population Movements. pp. 143-157 in The Global Origins and Developments of Seafaring. A. Anderson, J. H. Barrett & K. V. Boyle, Eds., ISBN: 978-1-902937-52-6, McDonald Institute for Archaeological Research, Cambridge, UK.

2009. Tishkoff, S. A., F. A. Reed, F. R. Friedlaender, C. Ehret, A. Ranciaro, et al. The Genetic Structure and History of Africans and African Americans. Science 324: 1035-1044. doi:10.1126/science.1172257

2008. Milinski, M., R. Sommerfeld, H.-J. Krambeck, F. A. Reed and J. Marotzke. The collective risk social dilemma, and the prevention of simulated dangerous climate change. Proceedings of the National Academy of Sciences USA 105: 2291-2294. doi:10.1073/pnas.0709546105

2008. Reed, F. A. Are Humans Still Evolving? In Encyclopedia of Life Sciences: Handbook of Human Molecular Evolution, D. N. Cooper & H. Kehrer-Sawatzki, Eds., John Wiley & Sons, Ltd., Chichester, UK. http://www.els.net doi:10.1002/9780470015902.a0020794

2008. Friedlaender, J. S., F. R. Friedlaender, F. A. Reed, K. K. Kidd, J. R. Kidd, et al. The Genetic Structure of Pacific Islanders. PLoS Genetics 4: e19. doi:10.1371/journal.pgen.0040019

2007. Tishkoff, S. A., M. K. Gonder, B. M. Henn, H. M. Mortensen, N. Fernandopulle, et al. History of click-speaking populations of Africa inferred from mtDNA and Y chromosome genetic variation. Molecular Biology and Evolution 24: 2180-2195. doi:10.1093/molbev/msm155

2007 Reed, F. A. Two-locus epistasis with sexually antagonistic selection: A genetic Parrondo’s paradox. Genetics 176: 1923-1929. doi:10.1534/genetics.106.069997

2007. Gonder, M. K., H. M. Mortensen, F. A. Reed, A. de Sousa and S. A. Tishkoff. Whole mtDNA Genome Sequence Analysis of Ancient African Lineages. Molecular Biology and Evolution 24: 757-768. doi:10.1093/molbev/msl209

2007. Tishkoff, S. A., F. A. Reed, A. Ranciaro, B. F. Voight, C. C. Babbitt, et al. Convergent adaptation of human lactase persistence in Africa and Europe. Nature Genetics 39: 31-40.
doi:10.1038/ng1946

2006. Reed, F. A. and S. A. Tishkoff. African human diversity, origins and migrations. Current Opinion in Genetics & Development 16: 597-605. doi:10.1016/j.gde.2006.10.008

2006. Reed, F. A. and C. F. Aquadro. Mutation, selection and the future of human evolution. Trends in Genetics 22: 479-484. doi:10.1016/j.tig.2006.07.005

2006. Kontanis, E. J. and F. A. Reed. Evaluation of real-time PCR amplification effciencies to detect inhibitors. Journal of Forensic Sciences 51: 795-804. doi:10.1111/j.1556-4029.2006.00182.x

2006. Reed, F. A. and S. A. Tishkoff. Positive selection can create false hotspots of recombination. Genetics 172: 2011-2014. doi:10.1534/genetics.105.052183

2005. Reed, F. A., J. M. Akey and C. F. Aquadro. Fitting background-selection predictions to levels of nucleotide variation and divergence along the human autosomes. Genome Research 15: 1211-1221. doi:10.1101/gr.3413205

2005. Reed, F. A., R. G. Reeves and C. F. Aquadro. Evidence of susceptibility and resistance to cryptic X-linked meiotic drive in natural populations of Drosophila melanogaster. Evolution 59: 1280-1291. doi:10.1111/j.0014-3820.2005.tb01778.x

2004. Reed, F. A. Characterizing Diversity Reducing Selection in Humans and Fruitflies. Ph.D. Dissertation, Cornell University, Ithaca, NY. http://wwwlib.umi.com/dissertations/fullcit/3149436

2003. Reed, F. A., E. J. Kontanis, K. A. R. Kennedy and C. F. Aquadro. Ancient DNA prospects from Sri Lankan highland dry caves support an emerging global pattern. American Journal of Physical Anthropology 121: 112-116. doi:10.1002/ajpa.10211

2001. Aquadro, C. F., V. L. Bauer DuMont and F. A. Reed. Genome-wide variation in the human and fruitfly: a comparison. Current Opinion in Genetics & Development 11: 627-634. doi:10.1016/S0959-437X(00)00245-8

Invited Talks

2015 Reed, F. A. Genetic Engineering for Species Conservation Applications in Hawai`i. Okinawa Institute of Science and Technology, Okinawa, Japan. August.

2014. Reed, F. A. Genetic Engineering for Species Conservation Applications in Hawai`i. ConGenOmics Workshop. Uppsala, Sweden. March. (PDF)

2014. Reed, F. A. Genetic Engineering for Species Conservation Applications in Hawai`i. Department of Entomology, North Carolina State University, Raleigh, NC. March. (PDF)

2012. Reed, F. A. Genetically transforming a population using underdominance. Hawai`i Institute of Marine Biology, Kane'ohe, Hawai`i, September.

2011. Reed, F. A. Underdominance Predictions and Genetically Transforming a Population. Department of Zoology, University of Hawai`i at Manoa. February. (PDF)

2011. Reed, F. A. Underdominance Predictions and Population Transformations. Department of Biology, Ludwig Maximilian University, Munich, Germany. January.

2010. Reed, F. A. On Gene-Culture Coevolution: Language and Music. Technological, dialectological and theoretical linguistics meeting. Department of Lingusitics and Scandinavian Studies. University of Oslo, Oslo, Norway. September.

2010. Reed, F. A. On Gene-Culture Coevolution: Adult Lactose Tolerance in Africa. Department of Tumor Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway. September. (PDF)

2010. Reed, F. A. Modern human migrations: the First 200,000 years. Interdiszipliaeres Dialogforum, Migrations: Interdisciplinary Perspectives. University of Vienna, Vienna, Austria. July.

2009. Reed, F. A. Underdominance Predictions and Population Transformations. Institute for Population Genetics, University of Veterinary Medicine Vienna. Vienna, Austria. November. (PDF)

2009. Reed, F. A. Underdominance Predictions and Population Transformations. Department of Evolutionary Biology, Uppsala University, Uppsala, Sweden. October.

2009. Reed, F. A. Underdominance and Population Transformations. Mind the gap: joining theoretical and empirical population genetics. VW-Stiftung Workshop, Freiburg, Germany. October.

2008. Reed, F. A. and M. Schoenbrunn. Gene-Culture Coevolution: A Focus on Music in Africa. Geniale Science Festival, Department of Art and Music, Beliefeld University, Beliefeld, Germany. October.

2007. Reed, F. A. The Structure and Migrations of Human Populations in Africa. The African Society of Human Genetics, Cairo, Egypt. November.

2007. Reed, F. A. The Genetic Structure of Human Populations in Africa. Aquavit V meeting, The Max Planck Institute for Evolutionary Biology, Ploen, Germany. March.

2007. Reed, F. A. A Microsatellite Based Likelihood-Approximation with Simultaneous Mutation, Demographic and Selective Inference. The Institute for Genetics, University of Cologne, Cologne, Germany. March.

2007. Reed, F. A. Using microsatellites to characterize human population structure in Africa and simultaneously infer selection and demography in Drosophila. The Department of Genetics, North Carolina State University, Raleigh, North Carolina. January.

2002. Reed, F. A. Levels of human polymorphism are consistent with weak background-selection. The Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. December.

2000. Reed, F. A., and C. F. Aquadro. Detecting recent selection in humans using microsatellites. LSU Ecology & Evolution Department, Baton Rouge, Louisiana. November.

2000. Reed, F. A. The genetic history of the Jacob breed of sheep. National meeting of the Jacob Sheep Breeders Association, Gilbertsville, New York. June.

Honors and Awards

2015. Nominated for an Excellence in Teaching award in the College of Natural Sciences, University of Hawai`i at Manoa, Honolulu, HI.

2014. Nominated for an Excellence in Teaching award in the College of Natural Sciences, University of Hawai`i at Manoa, Honolulu, HI.

2007. Selected for a competitive award from the U. S. National Institutes of Health, Loan Repayment Program for Health Disparities Research. (forced to decline because of subsequent employment outside of the U.S.)

2004. Supported by an award from The Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD.

2001. Fitch prize finalist. Reed, F. A., and C. F. Aquadro. The effects of deleterious mutations on levels of variation in the human genome. Annual meeting of the Society for Molecular Biology and Evolution. July 2001, Athens, GA.

2000. Selected for the NSF Training Grant "Evolution from DNA to the Organism: The Interface between Evolutionary Biology and the Mathematical Sciences." Administered by the Department of Biometrics, Cornell University, Ithaca, NY.

2000. Fitch prize finalist. Reed, F. A., and C. F. Aquadro. Detecting recent selection in humans using microsatellites. Joint meetings of the Society for Molecular Biology and Evolution & the American Genetics Association. June 2000, New Haven, CT.

1996. Recipient of a competitive summer semester tuition waiver for students of Cherokee heritage. Cherokee Archaeology Field School. Warren Wilson Site, Swannanoa, NC.

1996. Elected class speaker for the Warren Wilson College commencement ceremony. May 1996, Swannanoa, NC.

1996. The Edward C. Jeffrey Award in Biological Sciences. Department of Biology, Warren Wilson College, Swannanoa, NC.

1996. First Place in Undergraduate Research Presentations, Biological Sciences IV. The 93rd annual meeting of the North Carolina Academy of Science, March, Wake Forest University, Winston-Salem, NC.

1994. CRC Press Freshman Chemistry Award. Warren Wilson College, Swannanoa, NC.

Just for fun

My Bacon Number: 3
Elias Koteas and Kevin Bacon appeared in Novocaine (2001).
Lance Lewman and Elias Koteas appeared in Shot in the Heart (2001).
I appeared in Mastodon in your Backyard (Discovery Channel, 2001) which was narrated by Lance Lewman.
(All in the same year, which must give me extra points!)

Erdös number: 4 (F.A. Reed - C.F. Aquadro - R.T. Durrett - K.L. Chung - P. Erdos)

My Erdős–Bacon Number: 7

Academic Lineage

Several branches exist forking apart and coming back together; this is just one path connecting advisors, influences, and students. Again, this is just for fun and should not be taken too seriously.

Diego de Acebo, Spanish theologian, University of Palencia
Dominic de Guzmán (1170–1221) Spanish Founder of the Dominican order, University of Palencia
Reginald of Orleans ( -c.1220) French Dominican friar, University of Paris
Jordan of Saxony (c.1190–1237) German, Dominican leader, and grammarian, University of Paris
Albertus Magnus (1193-1280) German philosopher and theologian, Doctor universalis, University of Padua
Peter of Spain, Iberian logician and medical author, University of Paris
John Duns Scotus (1266 – 1308) Scottish philosopher-theologian, Doctor Subtilis, Oxford University
William of Ockham (1287 – 1347) English Franciscan friar and philosopher, known for "Occam's razor", Exeter College, Oxford University
Gregory of Rimini ( – 1358) Italian philosopher and theologian, Doctor acutus, University of Paris
Pierre d'Ailly (1351 – 1420) French astrologer and Roman Catholic Cardinal, University of Paris
Paul of Venice (1369–1429) Augustinian friar, philosopher, and logician, University of Padua
Gaetano da Thiene (1387–1465) Italian philosopher and physician, University of Padua
Pietro Roccabonella Veneziano (1427-1491) physician, University of Padua
Niccolò Leoniceno (1428–1524) Italian philosopher and physician. He translated many ancient medical texts. University of Padua
Antonio Musa Brassavola (1500–1555) Italian physician, University of Ferrara
Gabriele Falloppio (1523–1562) Italian physician and anatomist, University of Padua
Hieronymus Fabricius (Girolamo Fabrizi) (1537–1619) Italian anatomist, surgeon, and "the father of embryology", University of Padua
Jan Jesenius (1566–1621) Hungarian-German anatomist, surgeon, and politician, University of Leipzig
Daniel Sennert (1572–1637) German physician and chemist, University of Wittenberg
Werner Rolfinck (1599–1673) German physician, chemist, and botanist, University of Jena
Augustin Heinrich Fasch (1639-1690) physician, University of Jena
Johann Gottfried von Berger (1659-1736) German physician, University of Jena
Augustin Friedrich Walther (1688–1746) German physician, anatomist, and botanist, University of Wittenberg
Christian Gottlieb Ludwig (1709–1773) German physician and botanist, University of Leipzig
Johann Carl Gehler, (1732–1796) German physician, mineralogist and anatomist, University of Leipzig
Abraham Gottlob Werner (1749–1817) German geologist, proposed the theory of Neptunism, Freiberg University of Mining and Technology
A. von Humboldt (1769–1859) German naturalist, explorer, and geographer, Freiberg University of Mining and Technology
L. Agassiz (1807–1873) Swiss-American biologist and geologist, Harvard University
W. K. Brooks (1848–1908) American zoologist, Johns Hopkins University
T. H. Morgan (1866–1945) American geneticist, Columbia University
T. Dobzhansky (1900–1975) Ukrainian-American geneticist and evolutionary biologist, the modern evolutionary synthesis, Cali. Inst. of Tech.
F. Ayala Spanish-American evolutionary biologist, philosopher, and Dominican priest, University of California, Irvine
J.C. Avise American evolutionary geneticist, University of Georgia
C.F. Aquadro, American population geneticist, Cornell University
F.A. Reed, me, University of Hawaiʻi at Mānoa

Here is a link to an alternative (and ridiculously large) academic genealogy plot showing the branching process.